Effect of intravenous and intraperitoneal lignocaine on post operative pain scores in dogs undergoing ovariohysterectomy

The study was conducted in twelve female dogs of different breeds, randomly divided into two groups of six dogs each. All dogs underwent a comprehensive pre-anaesthetic evaluation prior to surgery. One hour before the procedure, the dogs received firocoxib orally. Pre-anaesthetic medication included injections of xylazine and buprenorphine, followed by induction with ketamine and midazolam. In Group I, lignocaine was administered during induction followed by a constant rate infusion (CRI), while in Group II, lignocaine was applied directly to the peritoneal cavity and viscera during surgery. Anaesthesia was maintained with isoflurane in both the groups. The quality of sedation, induction and recovery from anaesthesia was noted as excellent in both groups. Haematological and serum biochemical parameters varied within normal acceptable ranges and showed no significant differences between the groups. Electrocardiographic parameters, blood pressure values and blood gas parameters also remained within normal limits, without significant differences between the groups. Pain scores were lower in Group II compared to Group I, although the difference was not statistically significant. Both multimodal anaesthetic protocols proved effective in managing postoperative pain in dogs. Keywords: Pain, multimodal anaesthesia, multimodal analgesia, OHE, GCMPS