Predictive Models of Cholesterol Levels through Protein Expression Patterns

This review article is designed to analyze pattern variations in protein expression in order to develop algorithms for predicting cholesterol levels. Considering the critical role cholesterol plays in health assessments, the current study evaluates the literature comprehensively so as to track the current state of research in this area. The background establishes the importance of cholesterol while pointing out the limitations of traditional techniques of prediction. The literature review covers the latest methodologies, including mass spectrometry and machine learning algorithms. Two categories the studies are divided into: proteomic approaches and computational models. It specifically states that special attention has been given to omics data integration in further work to improve the accuracy of predictive models. The critical analysis study highlighted some challenges in existing methodologies and gave indicative future directions that help develop the improvement and optimization methodologies of prediction models based on protein expression patterns. This could make a big difference in cholesterol prediction and provide more realistic and personalized health assessments.

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Publication Details

Published
2024-10-25
DOI
https://doi.org/10.1109/icisaa62385.2024.10829210
Primary Topic
Lipoproteins and Cardiovascular Health
Type
article
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article

Predictive Models of Cholesterol Levels through Protein Expression Patterns

Varsha Rani, G. Vasavi, Sasibhushana Rao Pappu, Bharath Ramesh et al.
Lipoproteins and Cardiovascular Health
article

Predictive Models of Cholesterol Levels through Protein Expression Patterns

Varsha Rani, G. Vasavi, Sasibhushana Rao Pappu, Bharath Ramesh, Balajee Maram, M. Lokesh Reddy
article en

Abstract

This review article is designed to analyze pattern variations in protein expression in order to develop algorithms for predicting cholesterol levels. Considering the critical role cholesterol plays in health assessments, the current study evaluates the literature comprehensively so as to track the current state of research in this area. The background establishes the importance of cholesterol while pointing out the limitations of traditional techniques of prediction. The literature review covers the latest methodologies, including mass spectrometry and machine learning algorithms. Two categories the studies are divided into: proteomic approaches and computational models. It specifically states that special attention has been given to omics data integration in further work to improve the accuracy of predictive models. The critical analysis study highlighted some challenges in existing methodologies and gave indicative future directions that help develop the improvement and optimization methodologies of prediction models based on protein expression patterns. This could make a big difference in cholesterol prediction and provide more realistic and personalized health assessments.

Aditya Birla (India) (IN), GITAM University (IN)
Zero hunger
Openalex Percentile: Top 54%
Lipoproteins and Cardiovascular Health
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