Testicular function in postpubertal patients with growth hormone deficiency: A prospective controlled study
This is the first evidence of mildly impaired sperm parameters and TV in GHD patients compared to healthy controls. The integrity of the GH-IGF1 axis in prepuberty is important for achieving normal testicular function in adulthood. Evaluating testicular growth over time in GHD children and measuring TV and sperm parameters in postpubertal GHD boys is advisable.
Authors
- Andrea Crafa (ORCID: https://orcid.org/0000-0002-8311-9095)
- Sabrina Sapienza
- Aldo Eugenio Calogero (ORCID: https://orcid.org/0000-0001-6950-335X)
- Sandro La Vignera (ORCID: https://orcid.org/0000-0002-7113-2372)
- Rossella Cannarella (ORCID: https://orcid.org/0000-0003-4599-8487)
- Roberto Curto (ORCID: https://orcid.org/0009-0003-5395-8140)
- Rosita A. Condorelli
- Manuela Caruso
Institutions
- Cleveland Clinic (US)
- University of Catania (IT)
Publication Details
- Journal
- Journal of Clinical & Translational Endocrinology
- Published
- 2025-01-16
- DOI
- https://doi.org/10.1016/j.jcte.2025.100383
- Citations
- 1
- Primary Topic
- Sexual Differentiation and Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.81