Fluorescent Macrocyclic Arenes: Synthesis and Applications

Abstract Fluorescent macrocyclic arenes have attracted increasing interest in macrocyclic and supramolecular chemistry due to their exceptional photophysical properties and versatile applications. Classical macrocyclic arenes modified with fluorescent groups at the upper or bottom rims have long provided valuable platforms across various fields. Recently, a large number of novel fluorescent macrocyclic arenes directly composed of polycyclic aromatic or heteroaromatic building blocks including naphthalene, anthracene, tetraphenylethene, pyrene, fluorene, carbazole, acridan, phenothiazine, coumarin, triphenylamine, benzothiadiazole and so on, have been reported, and they have shown specific fluorescent property, and also exhibited broad applications in molecular recognition, sensing, bioimaging and functional materials. In this review, we focus on the recent advances in the synthesis and applications of fluorescent macrocyclic arenes containing polycyclic aromatic or heteroaromatic skeletons emerged in the past decade. By categorizing these fluorescent macrocyclic arenes based on the different building blocks, this review provides a comprehensive summary of their synthesis, properties and applications.