Comparative Evaluation of Nebulizer Devices Present in Market and Factors Influencing Nebulizer Performance

Pharmaceutical aerosols are frequently used in respiratory drug delivery for the treatment of various pulmonary conditions. A nebulizer device transforms fluid drug into an awfully fine mist that an individual inhalevia mask or mouthpiece. Administering medication in this manner allows it to be directed straight into the lungs and facilitated to the desired site. Traditional pMDIs and DPIs have long been preferred but come with lots of performance issues and patient factors. However, newer nebulization advancementsdeveloped in the last several decades, various nebulizers can now be used for portable use outside of the home, where local medicine administration to the lungs lowers dosage requirements and adverse effects as compared to alternative delivery methods. The primary objective behind the current article is to review the performance of various nebulizers prescribed in the market and their impact on patient safety. The current review deals with the generations of nebulizer devices present in the market along with their significances. The review also covers the mechanism with which these nebulizers operate, and the most important is a difference in the nebulization time of different nebulizers, which directly affects the drug delivery to the site of action.This review covers how important it is to use recommended nebulizers as a difference in nebulization time by using non-recommended nebulizer can lead to hyper or hypo delivery of doses to the site of action, thus leading to resistance and is likely to compromise the safety of patients.