Prevention of Acute Adhesive Intestinal Obstruction in the Postoperative Period
Introduction: Peritoneal adhesions are fibrinopurulent substances that link abdominal organs, which often cause clinical problems. Research seeks to examine the effectiveness of anterolateral transdermal myostimulation in reducing the postoperative adhesion formation and preventing AAIO.Method: This study investigates transdermal myostimulation efficacy in preventing postoperative adhesions through a two-phase experiment using piglets (n=20) and human patients (n=100). Data analysis was conducted using SPSS 26.Results: In piglets, the experimental group exhibited only mild adhesions (100%) with a significantly lower mean number of adhesions (3.5 ± 0.53) compared to the control group (8.1± 0.32). The intervention delayed adhesion formation (8.1 ± 1.3 days vs. 5.5 ± 0.85 days; t =-5.332, p = .000). In human patients, the experimental group showed a significantly lower incidence of adhesions (30.0% vs. 56.0%, p = .007) and obstruction symptoms (16.0% vs. 42.0%, p = .004). Improved outcomes included higher EGEG scores (80.0% vs. 32.0%, p = .000), reduced postoperative complications (20.0% vs. 42.0%, p = .015), and shorter hospital stays (1.86 ± 0.54 days vs. 2.78 ± 0.42 days; t = 9.579, p = .000). The intervention effectively reduced adhesion-related complications and enhanced recovery.Conclusion: The research showed that the experimental intervention significantly reduced postoperative adhesions in piglets and human patients. The like findings with either model indicate that this approach would be a useful way of mitigating postoperative adhesions and improving patient outcomes
Authors
- Berik Dzhumabekov (ORCID: https://orcid.org/0000-0002-3811-4244)
- Ildar Ravisovich Fakhradiyev (ORCID: https://orcid.org/0000-0003-0528-3874)
- А.Т. ДЖУМАБЕКОВ (ORCID: https://orcid.org/0000-0002-3502-4411)
- Т.Р. ФАЗЫЛОВ (ORCID: https://orcid.org/0000-0001-9604-5155)
- Б.К. АЙТБЕКОВ (ORCID: https://orcid.org/0009-0006-6241-0410)
- Ernis Alybaev (ORCID: https://orcid.org/0009-0000-5647-3809)
Institutions
- Kazakh National Medical University (KZ)
- Kazakhstan Medical University (KZ)
- Ministry of Health of Kyrgyzstan (KG)
- Karamay Central Hospital (CN)
- National Center of Cardiology and Internal Medicine (KG)
Publication Details
- Journal
- Salud Ciencia y Tecnología
- Published
- 2024-12-30
- DOI
- https://doi.org/10.56294/saludcyt2024.1293
- Primary Topic
- Intestinal and Peritoneal Adhesions
- Type
- article
- Field-Weighted Citation Impact
- 0.00