Abstract 030: Novel CT‐based Biomarkers for Patients with Anterior Circulation Stroke and Large Infarct Core

Patients with acute ischemic stroke (AIS) due to anterior circulation large vessel occlusion (LVO) can benefit from endovascular therapy (EVT) regardless of the Alberta Stroke Program Early CT Score (ASPECTS). Net water uptake (NWU) is a novel biomarker that measures edema and tissue injury from the degree of hypoattenuation on non‐contrast CT (NCCT). Using our recently developed algorithm for automated NWU calculations, and a newly proposed Visual Hypodensity Score (VHS, Table 1), we evaluated whether these new biomarkers perform better than ASPECTS to distinguish which patients with large core will have functional independence at 90 days.