Abstract 389: Real World Time to Thrombolytic Treatment Mirror Randomized Mobile Stroke Unit Trial

Randomized trials are the gold standard for testing novel approaches to established treatment strategies. However, the controlled setting inherent to trials may not accurately reflect the complexities of real‐world clinical practice. BEST‐MSU demonstrated that mobile stroke units (MSUs) accelerate thrombolytic treatment for acute ischemic stroke and improve clinical outcomes compared to standard management by Emergency Medical Services (EMS). We aimed to determine whether observed real‐world data from MSU patients treated with intravenous thrombolysis (IVT) (RW cohort) demonstrated results comparable to IVT‐treated patients from the BEST‐MSU trial (RT cohort).

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Publication Details

Journal
Stroke Vascular and Interventional Neurology
Published
2024-11-01
DOI
https://doi.org/10.1161/svin.04.suppl_1.389
Primary Topic
Acute Ischemic Stroke Management
Type
article
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article

Abstract 389: Real World Time to Thrombolytic Treatment Mirror Randomized Mobile Stroke Unit Trial

Asif Ali, Ritvij Bowry, James C. Grotta, Andrew D. Barreto et al.
Stroke Vascular and Interventional Neurology
Acute Ischemic Stroke Management
article

Abstract 389: Real World Time to Thrombolytic Treatment Mirror Randomized Mobile Stroke Unit Trial

Asif Ali, Ritvij Bowry, James C. Grotta, Andrew D. Barreto, Asha P. Jacob, David Persse, G. Rodney Meeks, Alexandra L. Czap, Irvan Trang, S. Parker, Benjamin Aiken, José-Miguel Yamal, M. Wang, Nicholas Delcimmuto
article en

Abstract

Randomized trials are the gold standard for testing novel approaches to established treatment strategies. However, the controlled setting inherent to trials may not accurately reflect the complexities of real‐world clinical practice. BEST‐MSU demonstrated that mobile stroke units (MSUs) accelerate thrombolytic treatment for acute ischemic stroke and improve clinical outcomes compared to standard management by Emergency Medical Services (EMS). We aimed to determine whether observed real‐world data from MSU patients treated with intravenous thrombolysis (IVT) (RW cohort) demonstrated results comparable to IVT‐treated patients from the BEST‐MSU trial (RT cohort).

Stroke Vascular and Interventional NeurologyVol. 4(S1)
University of Texas Health Science Center at Dallas (US), Memorial Hermann–Texas Medical Center (US), The University of Texas Health Science Center at Houston (US)
Good health and well-being
Openalex Percentile: Top 63%
Acute Ischemic Stroke Management
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Abstract 389: Real World Time to Thrombolytic Treatment Mirror Randomized Mobile Stroke Unit Trial — Asif Ali, Ritvij Bowry, et al. · Stroke Vascular and Interventional Neurology (2024) | TGRS Research Map | TGRS