Combinatorial Synthesis of Tetrasubstituted Alkenes and Related Compounds with Potential Anticancer Activity
The proposed combinatorial approach is applicable for the synthesis of diversified organic compound libraries and for the discovery of new tamoxifen analogues with an improved therapeutic profile.
Authors
- Petr Bartůněk (ORCID: https://orcid.org/0000-0002-6202-7650)
- Václav Eigner (ORCID: https://orcid.org/0000-0003-1014-3980)
- David Sedlák
- Marek Kořínek
- Miroslav Havránek
- Kateřina Nováčková
Institutions
- Czech Academy of Sciences (CZ)
- Apigenex (Czechia) (CZ)
- Institute of Molecular Genetics (RU)
- Czech Academy of Sciences, Institute of Molecular Genetics (CZ)
- University of Chemistry and Technology, Prague (CZ)
Publication Details
- Journal
- Combinatorial Chemistry & High Throughput Screening
- Published
- 2025-01-09
- DOI
- https://doi.org/10.2174/0113862073347827241104062749
- Primary Topic
- Chemical Synthesis and Analysis
- Type
- article
- Field-Weighted Citation Impact
- 0.00