INFLUENCE OF EPILEPSY ON THE COURSE AND OUTCOMES OF PREGNANCY

A retrospective analysis was conducted in 82 women with epilepsy. The course of pregnancy was analyzed in 58 women with epilepsy who took antiepileptic drugs during pregnancy - the main group, the comparison group - 24 pregnant women with drug-free remission of epilepsy. The etiology, pathogenesis, type and form of epilepsy were examined in the study groups. In the presence of epilepsy, other concomitant somatic pathology was present in 54 (93,1 %) pregnant women of the main and 21 (87,5 %) comparison groups, and the analyzed groups did not differ in terms of the two factors (p=0,409). There were no statistically significant differences between the groups in the incidence of anemia in pregnant women (59,6 % and 33,3 % (p=0,053), threatened miscarriage 39,7 % and 33,3 % (p=0,592), fetal growth restriction 12,1 % and 4,2 % (p=0,273). Chronic placental insufficiency in the main group was 11 (18,9 %) and 7 (29,2 %) in the comparison group (p=0,473), which indicated timely prevention in women of the main group