“Every Rose has its Thorn” – A Case Report on Olanzapine-induced Pancreatitis

This case report discusses the presentation and management of a 55-year-old woman with a history of episodic psychiatric illness, primarily treated with antipsychotics. Despite the patient’s prior positive response to risperidone and flupentixol with no significant adverse effects, she developed acute pancreatitis and severe acute respiratory distress syndrome soon after starting olanzapine therapy. Olanzapine-induced pancreatitis is a rare side effect, but the rapid onset and severe symptoms in this case highlights the importance of closely monitoring patients on antipsychotic medications, especially those with risk factors like age, gender, and metabolic issues. The patient’s atypical response to various antipsychotics and potential genetic factors contributing to drug sensitivity further highlights the complexity of managing psychiatric disorders and the importance of individualized treatment approaches.