[Clinicopathological Analysis of 14 Cases of Primary Pulmonary Lymphoepithelial Carcinoma].

PPLEC is a rare form of malignant lung tumor associated with Epstein-Barr virus (EBV) infection. The Regaud and Schmincke subtypes display distinct imaging and pathological characteristics. In the early stages of the disease, surgical intervention is the primary treatment method; however, for advanced stages, a multimodal treatment approach is utilized, resulting in a relatively favorable prognosis. Immunotherapy represents a promising and effective treatment modality for patients with middle to advanced stage disease exhibiting high PD-L1 expression levels.

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Publication Details

Journal
PubMed
Published
2024-11-20
DOI
https://doi.org/10.3779/j.issn.1009-3419.2024.101.29
Primary Topic
Multiple and Secondary Primary Cancers
Type
article
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article

[Clinicopathological Analysis of 14 Cases of Primary Pulmonary Lymphoepithelial Carcinoma].

Xiao Yuan, Anzhe Wang, Yu Kong, Liping Shen et al.
PubMed
Multiple and Secondary Primary Cancers
article

[Clinicopathological Analysis of 14 Cases of Primary Pulmonary Lymphoepithelial Carcinoma].

Xiao Yuan, Anzhe Wang, Yu Kong, Liping Shen, Yixuan Fang
article en

Abstract

PPLEC is a rare form of malignant lung tumor associated with Epstein-Barr virus (EBV) infection. The Regaud and Schmincke subtypes display distinct imaging and pathological characteristics. In the early stages of the disease, surgical intervention is the primary treatment method; however, for advanced stages, a multimodal treatment approach is utilized, resulting in a relatively favorable prognosis. Immunotherapy represents a promising and effective treatment modality for patients with middle to advanced stage disease exhibiting high PD-L1 expression levels.

PubMedVol. 27(11)
Soochow University (CN), First Affiliated Hospital of Soochow University (CN)
Multiple and Secondary Primary Cancers
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