Coal Worker's Pneumoconiosis-Targeted Lipidomics Reveals Aberrant Phospholipid Metabolism for Early-Stage Diagnosis.
The serum phospholipid profiles of patients with pneumoconiosis differed significantly from those of controls, including differences in PC, Lyso-PC, PI, PS, Lyso-PS, and PG. Among these, a diagnostic model incorporating PC (16:0), PC (16:0/18:1), PI (16:0/18:1), and PG (16:0) demonstrated superior screening efficiency.
Authors
- Yu Xiao (ORCID: https://orcid.org/0000-0002-9034-3386)
- Qingjun Qian
- Fangda Peng (ORCID: https://orcid.org/0000-0003-3589-4270)
- Jing Dai (ORCID: https://orcid.org/0000-0002-1889-6621)
- Yuzhen Feng (ORCID: https://orcid.org/0000-0002-0037-0963)
- Qicai Liu (ORCID: https://orcid.org/0000-0003-1766-9395)
- Chunguang Ding (ORCID: https://orcid.org/0000-0001-9051-7297)
- Yiwei Shi (ORCID: https://orcid.org/0000-0001-6764-1716)
- Huanqiang Wang (ORCID: https://orcid.org/0000-0002-2003-5230)
- Junyun Wang (ORCID: https://orcid.org/0000-0003-0573-7856)
- Xiaomei Kong (ORCID: https://orcid.org/0000-0003-4914-5916)
- Wenrong Wang
Institutions
- China National Center for Food Safety Risk Assessment (CN)
- National Institute for Occupational Health and Poison Control (CN)
Publication Details
- Journal
- PubMed
- Published
- 2024-12-27
- DOI
- https://doi.org/10.46234/ccdcw2024.279
- Primary Topic
- Occupational and environmental lung diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00