Study of the efficacy of implementing a protocol of perioperative antibiotic prophylaxis using digital technologies

Introduction. Following the modern method of perioperative antibiotic prophylaxis (PAP) is one of the ways to reduce the likelihood of developing antibiotic resistance and decrease the cost of pharmacological prevention of surgical infection. However, even now the real clinical practice of PAP often differs from the scientifically based one; there is often an excessive prescription of antibacterial agents or the choice of suboptimal drugs. Implementation of the PAP procedure using an intelligent program, chatbot, can increase the commitment of doctors to follow modern PAP. Purpose of the study. To develop and implement a mobile application, a chatbot for choosing a decision on the method of perioperative antibiotic prophylaxis based on the local PAP protocol of a multidisciplinary emergency hospital. Materials and research methods. A clinical and economic method: studying medical records of patients in emergency hospitals of surgical departments (trauma, surgery, neurosurgery, gynecology, urology, otorhinolaryngology). Python programming method, web application development. An administrative and documentary method: preparation and publication of orders and instructions for the medical institution on the procedure for implementing the protocol, monitoring compliance with the protocol. Results and discussion. Based on the existing local PAP protocol, standard solutions for choosing the PAP method have been compiled. Applications (Telegram chatbots) have been developed to facilitate this choice for a doctor making a decision on the PAP regimen. It has been established that commitment to the implementation of the PAP protocol continues to grow. This may be due to the lack of increased incidence of infection of the surgical wound despite a multiple reduction in the use of antimicrobial agents. The clarity and ease of use of algorithms for selecting PAP modes using digital technology were also revealed. The implementation of the PAP protocol was carried out with consistent information and administrative support. Conclusions. The implementation and maintenance of local protocol is effectively carried out using digital technologies. Following an evidence-based PAP protocol can achieve significant cost savings while maintaining the effectiveness of antimicrobial prophylaxis.