Cytomegalovirus Reactivation in Seropositive Kidney Transplant Recipients: A Retrospective Analysis of a UK Cohort.

Kidney transplant recipients ≥65 years were more likely to develop cytomegalovirus reactivation in the first 3 to 6 months posttransplant. Kidney allograft function at 12 months was significantly lower in recipients with cytomegalovirus reactivation. Our results suggest that universal cytomegalovirus drug prophylaxis in kidney recipients with cytomegalovirus seropositivity may help reduce cytomegalovirus reactivation and prevent associated adverse outcomes in older kidney transplant recipients.