Immunoassay using full-length and phage antibodies for antibiotic detection

The widespread use of antibiotics, leading to antibiotic resistance and the appearance of antibiotics in the environment and food, stimulates the development of new methods for monitoring antibacterial drugs in environmental objects. One of the promising areas for the development of methods for determining antibiotics belongs to sensor technologies. The key point in the development of sensory systems is the selection of a sensitive (recognizing) element. One of the most popular methods for recognizing antibiotics is the use of antibodies. The work presents the main immunosensory systems based on recording the “antigen-antibody” interaction and shows the advantages and disadvantages of polyclonal and monoclonal antibodies. The possibility of using phage antibodies to determine of antibiotics is described separately.