Management of children with heterozygous familial hypercholesterolaemia worldwide: a meta-analysis
Despite the efficacy of LLT in children with HeFH and the low occurrence of discontinuation-related adverse events, achieving LDL-C treatment goals was relatively rare, with large differences between the investigated countries. These results underscore the importance of considering early combination therapy of statins and ezetimibe, and PCSK9 inhibitors (if available) to attain LDL-C goals effectively.
Authors
- Gani Bajraktari (ORCID: https://orcid.org/0000-0003-0410-968X)
- Stanisław Surma (ORCID: https://orcid.org/0000-0001-8073-6664)
- Ivan Pećin (ORCID: https://orcid.org/0000-0003-4425-6473)
- Sefer Bytyqi (ORCID: https://orcid.org/0009-0001-4695-2117)
- Michael Y. Henein (ORCID: https://orcid.org/0000-0002-6089-5614)
- Dan Gaiță (ORCID: https://orcid.org/0000-0003-0320-6779)
- Agata Bielecka‐Dąbrowa (ORCID: https://orcid.org/0000-0001-6666-3999)
- Maciej Banach (ORCID: https://orcid.org/0000-0001-6690-6874)
- Francesco Paneni (ORCID: https://orcid.org/0000-0001-6483-7844)
- Raul Dias Santos (ORCID: https://orcid.org/0000-0002-9860-6582)
- Peter P. Tóth (ORCID: https://orcid.org/0000-0001-5810-5460)
- Niki Katsiki (ORCID: https://orcid.org/0000-0003-0894-2644)
- Carl J. Lavie (ORCID: https://orcid.org/0000-0003-3906-1911)
- Ioanna Gouni‐Berthold
- Arrigo F.G. Cicero (ORCID: https://orcid.org/0000-0002-4367-3884)
- Mutaz Al-Khnifsawi
- Ibadete Bytyçi
- Joanna Lewek (ORCID: https://orcid.org/0000-0001-8737-2453)
- Ali Ahmed (ORCID: https://orcid.org/0000-0002-6832-6424)
- Amirhossein Sahebkar
- Carlos Escobar (ORCID: https://orcid.org/0009-0003-7350-3098)
Institutions
- University of Siena (IT)
- John Paul II Catholic University of Lublin (PL)
- University Hospital Centre Zagreb (HR)
- Johns Hopkins University (US)
- Mashhad University of Medical Sciences (IR)
- Medical University of Silesia (PL)
- Universidade de São Paulo (BR)
- University of Cologne (DE)
- University of Zagreb (HR)
- International Hellenic University (GR)
- Georgetown University (US)
- University of New Orleans (US)
- George Washington University (US)
- European University Cyprus (CY)
- University of Zurich (CH)
- Johns Hopkins Medicine (US)
- Veterans Health Administration (US)
- Hospital Israelita Albert Einstein (BR)
- Hospital Universitario La Paz (ES)
- University Clinical Center of Kosovo (XK)
- Victor Babeș University of Medicine and Pharmacy Timișoara (RO)
- Biotechnology Research Center (IR)
- University Hospital of Zurich (CH)
- Azienda USL di Bologna (IT)
- CGH Medical Center (US)
- Medical University of Lodz (PL)
- University of Al-Qadisiyah (IQ)
- Institute e-Austria Timisoara (RO)
- Polish Mother’s Memorial Hospital Research Institute (PL)
- University Hospital Cologne (DE)
- Imperial College London (GB)
- University of Prishtina (XK)
- Saveetha University (IN)
- Umeå University (SE)
- University of Bologna (IT)
Publication Details
- Journal
- European Heart Journal Open
- Published
- 2024-12-24
- DOI
- https://doi.org/10.1093/ehjopen/oeaf001
- Citations
- 5
- Primary Topic
- Lipoproteins and Cardiovascular Health
- Type
- article
- Field-Weighted Citation Impact
- 2.86