Long‐Term Opioid Therapy and Risk of Opioid Overdose by Derived Clinical Indication in North Carolina, 2006–2018
Exposure to LTOT was associated with increased risk of opioid overdose in this population of privately insured patients using a rigorous definition of LTOT. These findings confirm the importance of guidelines to minimize duration of opioid therapy whenever possible.
Authors
- Kimberly A. Powers (ORCID: https://orcid.org/0000-0001-7980-9846)
- Shabbar I. Ranapurwala (ORCID: https://orcid.org/0000-0002-3944-3912)
- Bethany L. DiPrete (ORCID: https://orcid.org/0000-0003-1298-4433)
- Brian W. Pence (ORCID: https://orcid.org/0000-0001-7321-9538)
- Naoko Fulcher
- Audrey E. Pettifor (ORCID: https://orcid.org/0000-0002-3387-0817)
- Paul L. Delamater (ORCID: https://orcid.org/0000-0003-3627-9739)
Institutions
- University of North Carolina at Chapel Hill (US)
Publication Details
- Journal
- Pharmacoepidemiology and Drug Safety
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1002/pds.70090
- Primary Topic
- Opioid Use Disorder Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institutes of Health
- Centers for Disease Control and Prevention
- University of North Carolina at Chapel Hill
- National Institute on Drug Abuse
- National Institute of Allergy and Infectious Diseases
- Cecil G. Sheps Center for Health Services Research, University of North Carolina, Chapel Hill