Comparative evaluation of cytotoxic effects of a new biomaterial nanohydroxyapatite-lactoferrin, nanohydroxyapatite, mineral trioxide aggregate, and calcium-enriched mixture on human dental pulp stem cells

The findings indicate a significant correlation between the type of biomaterial used and its effect on cellular proliferation and viability, with time showing no significant influence. All the tested materials can be categorized as noncytotoxic materials, except NHA-LF in the highest concentration (1000%). The study suggests prioritizing low-dose NHA-LF for use.