Copper catalyzed C(sp<sup>3</sup>)–H/C(sp<sup>3</sup>)–H cross-coupling of arylacetic acid equivalents with methylarenes <i>via</i> α-carbonyl radicals
Arylacetic acid equivalents bearing a pyridine group undergo C(sp<sup>3</sup>)-H/C(sp<sup>3</sup>)-H cross coupling with diverse methylarenes in the presence of a copper based catalyst system. The reaction proceeds <i>via</i> the formation of α-carbonyl radicals giving access to α,β-diarylpropionic acids. Preliminary study suggests that the catalyst system is capable of transforming arylbenzyl ketones into 1,2,3-triaryl ketones.
Authors
- Bishwajit Ganguly (ORCID: https://orcid.org/0000-0002-9858-3165)
- Ashok Kumar Singh (ORCID: https://orcid.org/0000-0002-4853-2028)
- Sukalyan Bhadra (ORCID: https://orcid.org/0000-0003-1266-0930)
- Ajijur Rahaman (ORCID: https://orcid.org/0000-0001-5311-8481)
- Surjit Bhai (ORCID: https://orcid.org/0000-0002-1206-914X)
- Tulsi R. Patel (ORCID: https://orcid.org/0000-0001-6577-4400)
- Upendra Kumar Brijmohan Patel
Institutions
- Central Salt and Marine Chemicals Research Institute (IN)
- Academy of Scientific and Innovative Research (IN)
Publication Details
- Journal
- Chemical Communications
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1039/d4cc06801g
- Citations
- 3
- Primary Topic
- Catalytic C–H Functionalization Methods
- Type
- article
- Field-Weighted Citation Impact
- 2.81
Funders
- Science and Engineering Research Board
- Central Salt and Marine Chemicals Research Institute, Council of Scientific and Industrial Research