Review: Peran Zat Pelicin dalam Meningkatkan Efisiensi Proses Pembutan Sediaan Tablet Oral

The use of lubricants in oral tablet formulations has an important role in improving the efficiency of the production process. The lubricating agent helps to reduce friction between the particles and the mold wall, minimizing the risk of tablet damage during the printing and separation process. The study reviewed different types of lubricants, such as magnesium stearate and stearic acid, as well as their effects on the compactness, crushing time, and release of the active ingredient of the tablets. Optimal formulation is needed to avoid quality degradation due to excessive lubrication. Thus, the selection of the right lubricant is key to ensuring consistent tablet quality and a more efficient production process.

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Publication Details

Journal
Jurnal Lmu Farmasi dan Kesehatan/
Published
2024-11-21
DOI
https://doi.org/10.59841/an-najat.v2i4.1969
Primary Topic
Drug Solubulity and Delivery Systems
Type
article
Field-Weighted Citation Impact
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article

Review: Peran Zat Pelicin dalam Meningkatkan Efisiensi Proses Pembutan Sediaan Tablet Oral

Mikdat Adam, Veressa Alfianti, Nisa Aulia Sera, Della Prastyka et al.
Jurnal Lmu Farmasi dan Kesehatan/
Drug Solubulity and Delivery Systems
article

Review: Peran Zat Pelicin dalam Meningkatkan Efisiensi Proses Pembutan Sediaan Tablet Oral

Mikdat Adam, Veressa Alfianti, Nisa Aulia Sera, Della Prastyka, Putri Novianur Ramadhani, Nor Latifah
article en

Abstract

The use of lubricants in oral tablet formulations has an important role in improving the efficiency of the production process. The lubricating agent helps to reduce friction between the particles and the mold wall, minimizing the risk of tablet damage during the printing and separation process. The study reviewed different types of lubricants, such as magnesium stearate and stearic acid, as well as their effects on the compactness, crushing time, and release of the active ingredient of the tablets. Optimal formulation is needed to avoid quality degradation due to excessive lubrication. Thus, the selection of the right lubricant is key to ensuring consistent tablet quality and a more efficient production process.

Jurnal Lmu Farmasi dan Kesehatan/Vol. 2(4)
Universitas Muhammadiyah Banjarmasin
Openalex Percentile: Top 80%
Drug Solubulity and Delivery Systems
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