A Very Low–Carbohydrate Program in Adults With Metabolic Dysfunction–Associated Steatotic Liver Disease and Phospholipase Domain–Containing Protein 3 Risk Genotype: Pre-Post Intervention Study
Results suggest the feasibility, acceptability, and preliminary efficacy of the VLC intervention in adults with higher genetic risk for metabolic dysfunction-associated steatotic liver disease, although there is a need for further studies given the small sample size and the high risk of substantial biases in this small pilot study.
Authors
- Elizabeth K. Speliotes (ORCID: https://orcid.org/0000-0002-1002-4140)
- Laura R. Saslow (ORCID: https://orcid.org/0000-0003-3991-3205)
- Dina Mohamed Hafez (ORCID: https://orcid.org/0000-0002-2260-0299)
- Alison O’Brien (ORCID: https://orcid.org/0000-0002-8185-8118)
- Hovig Bayandorian (ORCID: https://orcid.org/0000-0003-4596-0323)
- Judith T. Moskowitz (ORCID: https://orcid.org/0000-0002-1399-3318)
- Jamie Krinock
- Jennifer Daubenmier (ORCID: https://orcid.org/0000-0001-5678-4068)
- Deanna J. Marriott (ORCID: https://orcid.org/0000-0002-7104-5682)
- Kaitlyn Raymond (ORCID: https://orcid.org/0009-0007-0134-623X)
- Antonino Oliveri
Institutions
- Northwestern University (US)
- University of Michigan (US)
- VA Ann Arbor Healthcare System (US)
- San Francisco State University (US)
Publication Details
- Journal
- JMIR Formative Research
- Published
- 2025-01-10
- DOI
- https://doi.org/10.2196/60051
- Citations
- 3
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 4.06