Altered Protein Structures and Neoepitopes in Lupus Neutrophils From Dysregulated Splicing of Messenger <scp>RNA</scp>
We conclude that aberrant mRNA splicing in SLE has the potential to affect both the function of granulocytes and to generate novel autoantigens.
Authors
- Hugh Alessi
- Robert K. Bradley (ORCID: https://orcid.org/0000-0002-8046-1063)
- Jose Mario Bello Pineda (ORCID: https://orcid.org/0000-0003-1417-9200)
- Alison Bays (ORCID: https://orcid.org/0000-0002-7193-6303)
- Tomas Mustelin (ORCID: https://orcid.org/0000-0001-5912-8840)
- James N. Jarvis (ORCID: https://orcid.org/0000-0002-1878-0717)
- Rayan Najjar (ORCID: https://orcid.org/0000-0002-9214-521X)
- Xiaoxing Wang (ORCID: https://orcid.org/0000-0003-2930-5265)
Institutions
- University of Washington (US)
- Fred Hutch Cancer Center (US)
- Seattle University (US)
Publication Details
- Journal
- ACR Open Rheumatology
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1002/acr2.11770
- Primary Topic
- Systemic Lupus Erythematosus Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institutes of Health
- Center for Scientific Review