Could Nocturnal Chronic Hypoxia Cause Ocular Surface Symptoms by Affecting Limbal Epithelial Cells in Patients With Obstructive Sleep Apnea?

In the literature, there is no study evaluating the effect of prolonged hypoxia on limbus epithelium as in patients with OSA. In this study, LET was measured to be statistically significantly thinner as the severity of OSA increased. Considering these results, it can be concluded that the proliferation of limbal stem cells is reduced in prolonged hypoxia.

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Publication Details

Journal
Cornea
Published
2025-01-10
DOI
https://doi.org/10.1097/ico.0000000000003791
Primary Topic
Ocular Surface and Contact Lens
Type
article
Field-Weighted Citation Impact
0.00
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article

Could Nocturnal Chronic Hypoxia Cause Ocular Surface Symptoms by Affecting Limbal Epithelial Cells in Patients With Obstructive Sleep Apnea?

Abdulkadir Can Çınar, Bilkay Serez Kaya, Ayça Küpeli Çınar, İlker Yılmam
Cornea
Ocular Surface and Contact Lens
article

Could Nocturnal Chronic Hypoxia Cause Ocular Surface Symptoms by Affecting Limbal Epithelial Cells in Patients With Obstructive Sleep Apnea?

Abdulkadir Can Çınar, Bilkay Serez Kaya, Ayça Küpeli Çınar, İlker Yılmam
article en

Abstract

In the literature, there is no study evaluating the effect of prolonged hypoxia on limbus epithelium as in patients with OSA. In this study, LET was measured to be statistically significantly thinner as the severity of OSA increased. Considering these results, it can be concluded that the proliferation of limbal stem cells is reduced in prolonged hypoxia.

CorneaVol. 44(12)
Trakya University (TR)
Good health and well-being
Openalex Percentile: Top 99%
Ocular Surface and Contact Lens
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