Nanostructured lipid carriers based mRNA vaccine leads to a T cell–inflamed tumour microenvironment favourable for improving PD-1/PD-L1 blocking therapy and long-term immunity in a cold tumour model
This work was supported by Inserm Transfert, la Région Auvergne Rhône Alpes, FINOVI, and the French Ministry of Higher Education, research and innovation (LipiVAC, COROL project, funding reference N° 2102992411).
Authors
- Fabrice Navarro (ORCID: https://orcid.org/0000-0003-2529-9558)
- Marion Mercey-Ressejac (ORCID: https://orcid.org/0000-0003-0667-2513)
- David Rageot
- Marie Escudé
- Patrice N. Marche (ORCID: https://orcid.org/0000-0002-8930-9340)
- Christine Charrat
- François Ghiringhelli (ORCID: https://orcid.org/0000-0002-5465-8305)
- Evelyne Jouvin‐Marche (ORCID: https://orcid.org/0000-0001-8616-138X)
- Julien Vollaire (ORCID: https://orcid.org/0000-0001-7001-4190)
- Thomas Decaens (ORCID: https://orcid.org/0000-0003-0928-0048)
- Véronique Josserand (ORCID: https://orcid.org/0000-0001-6733-3801)
- Valentin Dérangère (ORCID: https://orcid.org/0000-0002-6311-5628)
- Carole Fournier (ORCID: https://orcid.org/0000-0001-5735-0472)
- Séverine Escaich
- Alexis Leroy
- Amal Al Kadi
Institutions
- Centre National de la Recherche Scientifique (FR)
- Inserm (FR)
- Commissariat à l'Énergie Atomique et aux Énergies Alternatives (FR)
- Centre Hospitalier Universitaire de Grenoble (FR)
- CEA Grenoble (FR)
- Centre Georges François Leclerc (FR)
- Laboratoire d'Électronique des Technologies de l'Information (FR)
- Université Grenoble Alpes (FR)
Publication Details
- Journal
- EBioMedicine
- Published
- 2025-01-09
- DOI
- https://doi.org/10.1016/j.ebiom.2024.105543
- Citations
- 12
- Primary Topic
- Immunotherapy and Immune Responses
- Type
- article
- Field-Weighted Citation Impact
- 9.57
Funders
- Fondation Innovations en Infectiologie
- Infrastructures en Biologie Santé et Agronomie
- Agence Nationale de la Recherche
- Institut National de la Santé et de la Recherche Médicale
- Centre National de la Recherche Scientifique
- Inserm Transfert