[Study of the feasibility of polar body transfer combined with preimplantation genetic testing for blocking the intergenerational transmission of mitochondrial genetic diseases].
The PGT-MT technology can help families affected with mitochondrial diseases to have healthy offspring. PB1 transfer in combination with ICSI and PGT-MT holds the promise of turning waste into treasure and providing an alternative means of fertility for such families.
Authors
- Zhikang Zhang (ORCID: https://orcid.org/0000-0002-3024-1644)
- Chunmei Liang (ORCID: https://orcid.org/0000-0003-1639-7543)
- Dongmei Ji
- Weiwei Zou (ORCID: https://orcid.org/0000-0002-5963-7247)
- Kai Zong (ORCID: https://orcid.org/0000-0001-6413-759X)
- Dawei Chen (ORCID: https://orcid.org/0000-0002-3405-6753)
- Zhiguo Zhang (ORCID: https://orcid.org/0000-0003-1483-3321)
- Xianwei Wang (ORCID: https://orcid.org/0000-0002-1490-8736)
- Ning Zhang (ORCID: https://orcid.org/0000-0002-2680-1354)
- Yunxia Cao (ORCID: https://orcid.org/0000-0002-8715-0874)
- Yinan Du
- Xun Su (ORCID: https://orcid.org/0000-0002-8500-5008)
Institutions
- Anhui Medical University (CN)
- First Affiliated Hospital of Anhui Medical University (CN)
Publication Details
- Journal
- PubMed
- Published
- 2025-01-10
- DOI
- https://doi.org/10.3760/cma.j.cn511374-20240702-00366
- Citations
- 1
- Primary Topic
- Ethics and Legal Issues in Pediatric Healthcare
- Type
- article