[Protective effect of tumor necrosis factor receptor-associated factor 6 inhibitor C25-140 on acute kidney injury induced by diquat poisoning in mice].
TRAF6 inhibitor C25-140 can alleviate AKI induced by DQ poisoning in mice by regulating the Toll-like receptor 4 (TLR4)/TRAF6/NF-κB signaling pathway and downregulating the levels of inflammatory cytokines IL-1β, IL-6, and TNF-α.
Authors
- Nana Xu (ORCID: https://orcid.org/0000-0002-0367-0857)
- Manhong Zhou (ORCID: https://orcid.org/0000-0002-0824-1787)
- Tingting Huang (ORCID: https://orcid.org/0000-0001-8761-9700)
- Guosheng Rao
- Zhijie Zhao
- Renyang Ou
Institutions
- Zunyi Medical University (CN)
- Renaissance University (NG)
- Affiliated Hospital of Zunyi Medical College (CN)
Publication Details
- Journal
- PubMed
- Published
- 2024-12-01
- DOI
- https://doi.org/10.3760/cma.j.cn121430-20230906-00751
- Citations
- 1
- Primary Topic
- Paraquat toxicity studies and treatments
- Type
- article