A Design Science Approach to Modeling the V Gene Annotation Process

Design science is a methodology that addresses complex and evolving problems requiring a multidisciplinary approach. In this research, the methodology of design science is employed to construct a model for the process of V gene annotation in vertebrates. The process entails the identification of genes within a genome, the characterization of their structural elements, and the classification of their associated data. The model standardizes the work of molecular biologists, reducing time and errors. The methodology followed in this project includes rigor, relevance, and design cycles, developed in collaboration with experts in molecular biology and information systems. The result of the research is a BPMN model, validated by experts and trainees from the Centro de Investigación Sobre Enfermedades Infecciosas (CISEI) of the Instituto Nacional de Salud Pública (INSP) in Cuernavaca, Mexico.