Intrahepatic CD161<sup>hi</sup>CD8+T Cell Recruitment Has a Pathogenetic Potential in Chronic HBV Infection
During HBV infection, the intrahepatic recruitment of CD161+CD8+T cells was mainly CD161<sup>hi</sup>CD8+T cell subpopulation, which has a weak antiviral response, but increased pro-inflammatory effect, suggesting that CD161 may serve as a potential marker of liver-damaging T cells.
Authors
- J Li (ORCID: https://orcid.org/0009-0005-8619-7469)
- Futing Liu (ORCID: https://orcid.org/0000-0002-4495-520X)
- Wanlu Duan
- Qiyin Zong (ORCID: https://orcid.org/0009-0005-6981-2546)
- Qian Liu (ORCID: https://orcid.org/0000-0002-1937-0568)
- Qiang Zhou (ORCID: https://orcid.org/0009-0003-3757-9802)
- Hao Zhang (ORCID: https://orcid.org/0000-0002-4582-2556)
- Qin Wang (ORCID: https://orcid.org/0000-0001-8466-475X)
- Mengqi Ruan (ORCID: https://orcid.org/0009-0005-2103-831X)
- Zhi Duan
Institutions
- Anhui Medical University (CN)
- Second Affiliated Hospital of Anhui Medical University (CN)
Publication Details
- Journal
- Immunity Inflammation and Disease
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1002/iid3.70118
- Citations
- 1
- Primary Topic
- Hepatitis B Virus Studies
- Type
- article
- Field-Weighted Citation Impact
- 1.35
Funders
- National Natural Science Foundation of China
- Huazhong University of Science and Technology
- Tongji University
- Tongji Medical College, Huazhong University of Science and Technology