ATRIAL FIBRILLATION AND QUALITY OF LIFE OF PATIENTS RECEIVING VARIOUS GROUPS OF INDIRECT ANTICOAGULANTS

Abstract. Introduction. Atrial fibrillation remains one of the most common cardiac arrhythmias. Due to the world’s population aging, it is predicted that the number of patients with atrial fibrillation will reach 14-17 million people in Europe alone by 2030 and only continue to increase annually. The presence of this arrhythmia is associated with an increased risk of life-threatening thromboembolic complications. At the same time, a balanced and reasonable choice of anticoagulant therapy determines the prognosis of patients with atrial fibrillation. Aim. To analyze the physical and mental health components and coagulogram parameters in patients with atrial fibrillation, associated with receiving different groups of indirect anticoagulants. Materials and Methods. The study involved 50 patients diagnosed with atrial fibrillation and stayin in the therapeutic department of one of clinical hospitals in Kazan. All patients were divided into groups according to the form of atrial fibrillation, as well as into subgroups for taking warfarin, taking new oral anticoagulants, and without anticoagulant therapy being prescribed. Physical and mental health components were assessed out using the SF-36 questionnaire. Results and Discussion. The best indicators of the physical health component were found among patients with permanent atrial fibrillation taking warfarin, while the worst indicators were in the group of persistent atrial fibrillation who did not take anticoagulants at all. The mental health component was assessed higher in patients with persistent atrial fibrillation taking new oral anticoagulants, while the lowest values were observed among patients with persistent atrial fibrillation taking warfarin. According to the coagulogram data, there were no honestly significant differences among patients taking various groups of anticoagulants. Conclusions. In general, patients with atrial fibrillation may have insufficient adherence to anticoagulant treatment, which is associated with affordability, as well as the patient’s low awareness of atrial fibrillation complications. The data obtained indicate that the physical health component is higher and coagulogram indices are better in patients with permanent atrial fibrillation taking warfarin, whereas the best mental state is observed in patients taking new oral anticoagulants.