Inter-network Effective Connectivity During An Emotional Working Memory Task in Two Independent Samples of Young Adults
This study highlights the different patterns of DMN→CEN EC in conditions with high and low WM loads with and without ER, suggesting that in higher WM loads with ER, the integration of the DMN with the CEN is reduced to facilitate successful cognitive task performance. The findings also suggest that DMN→CEN and DMN→SN EC are significantly reduced in depressive and anxiety disorders, highlighting this pattern of reduced EC as a potential neural marker of these disorders.
Authors
- Richelle Stiffler (ORCID: https://orcid.org/0000-0001-7876-4586)
- Vaibhav A. Diwadkar (ORCID: https://orcid.org/0000-0001-6458-6969)
- Renata Rozovsky (ORCID: https://orcid.org/0000-0001-9544-8198)
- Alexander S. Skeba
- Genna Bebko
- Michele A. Bertocci (ORCID: https://orcid.org/0000-0002-3857-1226)
- Mary L. Phillips
- Haris Aslam
Institutions
- University of Pittsburgh (US)
- Wayne State University (US)
- University of Pittsburgh Medical Center (US)
Publication Details
- Journal
- Biological Psychiatry Cognitive Neuroscience and Neuroimaging
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1016/j.bpsc.2025.01.006
- Citations
- 3
- Primary Topic
- Functional Brain Connectivity Studies
- Type
- article
- Field-Weighted Citation Impact
- 4.29
Funders
- National Institute of Mental Health