A055: The Relationship Between Grip Strength and Quality of Life in theElderly Based

<bold>Background:</bold> The World Health Organization (WHO) has launched the "Decade of Healthy Ageing" from 2021 to 2030 to address the challenges of a rapidly ageing global population. The extension of human lifespan is a manifestation of social progress, but aging and increased longevity may be accompanied by problems such as reduced physical and mental abilities and increased risk of diseases, which affects quality of life (QOL). Grip as an indicator of strength and is associated with physical activity in older adults. It is readily applicable in clinical and community settings, and there is an association between grip strength and health-related quality of life, but the evidence for the strength of the association is inconsistent. Currently, there is no consensus on the threshold value of grip strength in older adults. The purpose of this study was to study the dose-effect relationship between grip strength and quality of life in the elderly, and to explore modifiable factors affecting quality of life in the elderly, so as to provide effective theoretical basis for realizing healthy aging. <bold>Methods:</bold> A total of 105 elderly people over 60 years old were selected from 3 communities in Beijing. Grip strength was measured by hand-held grip-o-meter and quality of life was assessed by SF-36 scale. Based on controlling confounding factors, the dose-effect relationship between grip strength and quality of life was analyzed with the restricted cubic spline model. <bold>Result:</bold> The results showed that there was a dose-effect relationship between grip strength level and physiological content score (<italic>P</italic> &lt; 0.01). Increased grip strength levels helped improve quality of life in older adults; however, grip strength was not significantly associated with mental health (<italic>P</italic> &gt; 0.05). When grip strength was lower than 27.7 KG (50th percentile), with the increase of the grip strength level, the physiological content comprehensive score of the elderly increased faster. When the total physical activity was greater than 27.7 KG, the improvement of the comprehensive physiological content score of the elderly slowed down. <bold>Conclusion:</bold> The findings help to understand the relationship between quality of life and grip strength in older adults and provides a reference for formulating policies to promote healthy aging. The maintenance of grip strength above 27.7 KG may help delay the decline of quality of life in the elderly and can be used as a reference index to evaluate the physical health of the elderly.