Formulation of different concentrations of nanosilver fluoride incorporated dentifrices, evaluation of its cytotoxicity and antimicrobial effect on Streptococcus mutans

The study concludes that NSF-incorporated dentifrices exhibit promising antimicrobial efficacy against Streptococcus mutans in a concentration-dependent manner. However, increasing concentrations of NSF also correlated with higher cytotoxicity levels in mammalian cells. Therefore, optimizing the concentration of NSF in dentifrices is crucial to balance antimicrobial benefits with biocompatibility.