PD-1 suppresses human CD38<sup>+</sup> circulating Tfr cells and regulates humoral immunity
Together, these data demonstrate the immunomodulatory role of PD-1 in restricting the differentiation and function of human cTfr cells and in regulating humoral immunity.
Authors
- Xiaolu Ma (ORCID: https://orcid.org/0000-0001-9514-6042)
- Yanchun Wang (ORCID: https://orcid.org/0000-0002-0203-7312)
- Cuncun Chen
- Ying Tong
- Suhong Xie (ORCID: https://orcid.org/0000-0003-1044-9373)
- Hui Zheng (ORCID: https://orcid.org/0000-0002-4325-4946)
- Renquan Lu
- Heng Zhang (ORCID: https://orcid.org/0000-0003-2655-6659)
- Lin Guo
Institutions
- Shanghai Medical College of Fudan University (CN)
- Fudan University Shanghai Cancer Center (CN)
Publication Details
- Journal
- Journal for ImmunoTherapy of Cancer
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1136/jitc-2024-010026
- Citations
- 2
- Primary Topic
- Cancer Immunotherapy and Biomarkers
- Type
- article
- Field-Weighted Citation Impact
- 2.09
Funders
- National Natural Science Foundation of China
- Fudan University
- Science and Technology Commission of Shanghai Municipality
- Shanghai Jiao Tong University
- School of Medicine, Shanghai Jiao Tong University