Circumstances of clinical fracture events with advancing age in older men
To characterize fracture circumstances by age at time of fracture among community-dwelling older men, we analyzed incident clinical fractures in the Osteoporotic Fractures in Men study. Participants were contacted every 4 mo to identify fractures confirmed by radiographic reports. Fractures were classified as fall- or non-fall-related and further categorized by degree of trauma: minimal (fall from ≤ standing height), moderate (fall on stairs, steps or curb), or severe (fall from > standing height) for fall-related fractures; and minimal (eg, coughing), moderate (eg, collisions with objects during normal activity without falling), or severe (eg, motor vehicle accident) for non-fall-related fractures. Of 2351 clinical fractures in 1424 men during an average follow-up of 9.9 yr, 12.7% occurred at age <75 yr, 15.7% at age 75-79 yr, 26.1% at age 80-84 yr, and 45.5% at age ≥85 yr. A total of 1891 fractures (80.4% of all fractures) were the result of a fall. The proportion of fall-related fractures steadily rose with increasing age at time of fracture, ranging from 65.8% in men <75 yr rising to 84.7% in men ≥85 yr (<i>p</i> < .001). Most fall-related fractures (76.4%) were due to minimal trauma; the proportion of all fractures due to a fall with minimal trauma steadily rose with increasing age (<i>p</i> < .001). In contrast, approximately half of non-fall-related fractures (53.5%) were due to severe trauma. The proportion of all fractures due to severe trauma (whether fall-related or not) declined with advancing age (<i>p</i> < .001). In conclusion, the most frequently occurring fracture circumstance in older men was a fall from ≤standing height. This circumstance was increasingly common with advancing age occurring in 7 of every 10 fractures in men ≥85 yr, while a fracture (fall-related or not) due to severe trauma was less common with advancing age. Findings have implications for development of fracture prevention strategies in older men.
Authors
- Sheena Patel (ORCID: https://orcid.org/0000-0002-0865-4266)
- Eric Orwoll (ORCID: https://orcid.org/0000-0002-8520-7355)
- Howard A Fink (ORCID: https://orcid.org/0000-0002-5985-5447)
- Lisa Langsetmo (ORCID: https://orcid.org/0000-0003-2245-1657)
- Douglas C. Bauer (ORCID: https://orcid.org/0000-0001-5261-7721)
- Jane A. Cauley (ORCID: https://orcid.org/0000-0003-0752-4408)
- Peggy M. Cawthon (ORCID: https://orcid.org/0000-0003-4938-9478)
- Kristine E. Ensrud (ORCID: https://orcid.org/0000-0002-9069-3036)
- John T. Schousboe (ORCID: https://orcid.org/0000-0002-9329-0750)
Institutions
- University of Minnesota (US)
- Oregon Health & Science University (US)
- University of Pittsburgh (US)
- University of California, San Francisco (US)
- California Pacific Medical Center (US)
- Minneapolis VA Health Care System (US)
- HealthPartners (US)
Publication Details
- Journal
- JBMR Plus
- Published
- 2025-01-10
- DOI
- https://doi.org/10.1093/jbmrpl/ziaf005
- Citations
- 2
- Primary Topic
- Bone health and osteoporosis research
- Type
- article
- Field-Weighted Citation Impact
- 3.44
Funders
- National Institutes of Health
- National Institute on Aging
- National Institute of Arthritis and Musculoskeletal and Skin Diseases
- National Center for Advancing Translational Sciences