Investigating T-cell-derived extracellular vesicles as biomarkers of disease activity, axonal injury, and disability in multiple sclerosis
In summary, the analysis of specific immune cell-derived EV subsets may provide a method to monitor disability accumulation, disease activity, and axonal injury in MS, while also providing insights into the pathophysiology and cellular/molecular mechanisms that influence progression.
Authors
- Sarah Anthony (ORCID: https://orcid.org/0000-0002-6230-8188)
- Craig S. Moore (ORCID: https://orcid.org/0000-0003-3333-435X)
- Stephanie N. Blandford (ORCID: https://orcid.org/0000-0002-3746-3653)
- Fraser Clift (ORCID: https://orcid.org/0000-0002-1355-6011)
- Neva J. Fudge (ORCID: https://orcid.org/0000-0001-9018-0698)
- Shane Arsenault (ORCID: https://orcid.org/0000-0002-4996-3436)
- Jennifer L Zagrodnik
- Lillian McGrath
- Mark Stefanelli
Institutions
- Memorial University of Newfoundland (CA)
- Université Bourgogne Franche-Comté (FR)
Publication Details
- Journal
- Clinical & Experimental Immunology
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1093/cei/uxaf003
- Citations
- 2
- Primary Topic
- Extracellular vesicles in disease
- Type
- article
- Field-Weighted Citation Impact
- 1.61
Funders
- Memorial University of Newfoundland
- Canadian Institutes of Health Research