Predictive role of ABC transporters in the efficacy of enfortumab vedotin for urothelial carcinoma
To our knowledge, this study is the first to show a correlation between ABC transporter expression and EV efficacy in urothelial carcinoma. Future research should focus on optimizing treatment strategies based on Nectin-4 and ABC transporter expression to improve outcomes.
Authors
- Takao Kamai (ORCID: https://orcid.org/0000-0002-7086-6964)
- Atsuko Takada‐Owada
- Kazuyuki Ishida (ORCID: https://orcid.org/0000-0002-2804-4588)
- Hidetoshi Kokubun
- Kohei Takei
- Masahiro Yashi (ORCID: https://orcid.org/0000-0002-6027-8106)
- Hironori Betsunoh (ORCID: https://orcid.org/0000-0002-7873-3568)
- Toshiki Kijima (ORCID: https://orcid.org/0000-0002-4380-9294)
- Hiroki Shimoda
- Toshitaka Uematsu
Institutions
- Tokyo Medical and Dental University (JP)
- Dokkyo Medical University (JP)
Publication Details
- Journal
- BJUI Compass
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1002/bco2.488
- Citations
- 4
- Primary Topic
- Bladder and Urothelial Cancer Treatments
- Type
- article
- Field-Weighted Citation Impact
- 8.03
Funders
- Japan Society for the Promotion of Science