Do Unresectable Giant Cell Tumors of Bone Treated With Denosumab Progress After Discontinuation of Treatment?

The findings of the present study suggest that discontinuation of denosumab in patients with unresectable GCTB is not necessarily associated with the progression of the disease. Further research is needed to determine how long denosumab should be administered to minimize the risk of recurrence.

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Publication Details

Journal
Cancer Reports
Published
2025-01-01
DOI
https://doi.org/10.1002/cnr2.70117
Citations
2
Primary Topic
Bone Tumor Diagnosis and Treatments
Type
article
Field-Weighted Citation Impact
3.34

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article

Do Unresectable Giant Cell Tumors of Bone Treated With Denosumab Progress After Discontinuation of Treatment?

P. Reguera Puertas, O. Pablos, Aida Orce, Ana M. Peiró et al.
2 citations
Cancer Reports
Bone Tumor Diagnosis and Treatments
3.34
article

Do Unresectable Giant Cell Tumors of Bone Treated With Denosumab Progress After Discontinuation of Treatment?

P. Reguera Puertas, O. Pablos, Aida Orce, Ana M. Peiró, Roberto García‐Maroto, I Chaves, Manuel Rubio Angulo, Miriam Maireles, Francisco J. González-González, Israel Pérez-Torres, Gregorio Valero‐Cifuentes, Paula González‐Rojo, Carolina de la Calva, Isidro Gracia, Juan Luis Cebrián, Antonio Valcárcel, María del Carmen Sanz, Pau Machado, María Luisa Fontalva, Luis Coll‐Mesa
article en
2 citations

Abstract

The findings of the present study suggest that discontinuation of denosumab in patients with unresectable GCTB is not necessarily associated with the progression of the disease. Further research is needed to determine how long denosumab should be administered to minimize the risk of recurrence.

Cancer ReportsVol. 8(1)
Hospital de Sant Pau (ES), Bellvitge University Hospital (ES), Hospital Clínico San Carlos (ES), Hospital Universitari i Politècnic La Fe (ES), Hospital Universitario Nuestra Señora de Candelaria (ES), Hospital Universitario Virgen de la Arrixaca (ES), Hospital Universitario Ramón y Cajal (ES)
Universidad de Oviedo
Good health and well-being
Openalex Percentile: Top 11%
Bone Tumor Diagnosis and Treatments
3.34
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