Green Biosynthesis, Characterization and Anticancer Activity of Sargassum cinctum Zinc Nanoparticles

This work aims at exploring the green synthesis of ZnO NPs from Sargassum cinctum; a brown marine macro algae. In the green synthesis of ZnO NPs, the bioactives present in Sargassum cinctum extract are capable of reducing and stabilising agents in the development of the said particles. As contrast to normal approaches, which usually involve the use of harmful chemicals to make nanoparticles, this technique is considered ecologically beneficial. The techniques of X-ray diffraction, scanning electron microscopy, and fourier transform infrared spectroscopy studies were employed to characterise the synthesised Sc-ZnO NPs. The crystalline structure, size distribution, and functional groups revealed in the seaweed extract were all supported by these studies and may be the reason of the nanoparticles' stability and biological activity. In order to determine the anti-cancerous property of the Sc-ZnO NPs, the particles were tested on breast cancer cell lines. The findings shown in the outcomes showed that Sc-ZnO NPs had the ability to suppress the growth of breast cancer cells. In general, this research indicates that Sc-ZnO NPs prepared with the help of green techniques based on Sargassum cinctum might be considered as a rather effective and environmentally friendly anticancer agent for breast cancer. The observations made allow for the possibility of the further use of these nanoparticles for the creation of new, environmentally-friendly anticancer agents that have less adverse effects on the environment and high selectivity towards cancer cells.

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Publication Details

Journal
Indian Journal of Biochemistry and Biophysics
Published
2025-01-01
DOI
https://doi.org/10.56042/ijbb.v62i2.14167
Primary Topic
Seaweed-derived Bioactive Compounds
Type
article
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Green Biosynthesis, Characterization and Anticancer Activity of Sargassum cinctum Zinc Nanoparticles

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Indian Journal of Biochemistry and Biophysics
Seaweed-derived Bioactive Compounds
article

Green Biosynthesis, Characterization and Anticancer Activity of Sargassum cinctum Zinc Nanoparticles

article en

Abstract

This work aims at exploring the green synthesis of ZnO NPs from Sargassum cinctum; a brown marine macro algae. In the green synthesis of ZnO NPs, the bioactives present in Sargassum cinctum extract are capable of reducing and stabilising agents in the development of the said particles. As contrast to normal approaches, which usually involve the use of harmful chemicals to make nanoparticles, this technique is considered ecologically beneficial. The techniques of X-ray diffraction, scanning electron microscopy, and fourier transform infrared spectroscopy studies were employed to characterise the synthesised Sc-ZnO NPs. The crystalline structure, size distribution, and functional groups revealed in the seaweed extract were all supported by these studies and may be the reason of the nanoparticles' stability and biological activity. In order to determine the anti-cancerous property of the Sc-ZnO NPs, the particles were tested on breast cancer cell lines. The findings shown in the outcomes showed that Sc-ZnO NPs had the ability to suppress the growth of breast cancer cells. In general, this research indicates that Sc-ZnO NPs prepared with the help of green techniques based on Sargassum cinctum might be considered as a rather effective and environmentally friendly anticancer agent for breast cancer. The observations made allow for the possibility of the further use of these nanoparticles for the creation of new, environmentally-friendly anticancer agents that have less adverse effects on the environment and high selectivity towards cancer cells.

Indian Journal of Biochemistry and Biophysics
Dr. Babasaheb Ambedkar Marathwada University (IN), Lata Medical Research Foundation (IN)
Zero hunger
Openalex Percentile: Top 100%
Seaweed-derived Bioactive Compounds
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