<scp>WTAP</scp> ‐Mediated <scp>m6A</scp> Modification of <scp>TRAIL</scp> ‐ <scp>DR4</scp> Suppresses <scp>MH7A</scp> Cell Apoptosis
This study suggests that WTAP-mediated m6A modification of TRAIL-DR4 suppresses MH7A cell apoptosis. This discovery offers a new focus and avenue for the clinical treatment of RA, while also extending our understanding of the pathophysiology of RA from the standpoint of m6A alteration.
Authors
- Xue Pang
- Hui Jiang (ORCID: https://orcid.org/0000-0003-2183-9430)
- Fan Chang
- Xiaoya Cui (ORCID: https://orcid.org/0000-0002-5383-2113)
- Fengxia Xu (ORCID: https://orcid.org/0000-0002-8807-499X)
Institutions
- Anhui University (CN)
- Anhui Medical University (CN)
- Anhui University of Traditional Chinese Medicine (CN)
- Second Affiliated Hospital of Anhui Medical University (CN)
Publication Details
- Journal
- International Journal of Rheumatic Diseases
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1111/1756-185x.70065
- Citations
- 5
- Primary Topic
- RNA modifications and cancer
- Type
- article
- Field-Weighted Citation Impact
- 4.03