Prospective Multicenter Evaluation of the <scp>MDS</scp> “Suggestive of <scp>PSP</scp>” Diagnostic Criteria
Most "suggestive of PSP" patients increased diagnostic certainty upon longitudinal follow-up, providing the first prospective multicenter validation of MDS-PSP diagnostic criteria. Our data support the design of trials tailored for these early-stage patients, suggesting the PSP rating scale and the diagnostic certainty increase rate as potential endpoint measures. © 2025 The Author(s). Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society.
Authors
- Andrea Quattrone (ORCID: https://orcid.org/0000-0003-2071-2083)
- Annika Spottke (ORCID: https://orcid.org/0000-0001-9854-2972)
- Gabor C. Petzold (ORCID: https://orcid.org/0000-0002-0145-8641)
- Frederic Brosseron (ORCID: https://orcid.org/0000-0003-3137-7516)
- Johannes Levin (ORCID: https://orcid.org/0000-0001-5092-4306)
- Björn Falkenburger (ORCID: https://orcid.org/0000-0002-2387-526X)
- Thomas Gasser (ORCID: https://orcid.org/0000-0002-1069-1146)
- Günter U. Höglinger (ORCID: https://orcid.org/0000-0001-7587-6187)
- Johannes Prudlo (ORCID: https://orcid.org/0000-0002-7932-5929)
- Nicolai Franzmeier (ORCID: https://orcid.org/0000-0001-9736-2283)
Institutions
- University Hospital Bonn (DE)
- German Center for Neurodegenerative Diseases (DE)
- LMU Klinikum (DE)
- Magna Graecia University (IT)
- Munich Cluster for Systems Neurology (DE)
- Hertie Institute for Clinical Brain Research (DE)
- University Hospital Carl Gustav Carus (DE)
- University of Rostock (DE)
- Technische Universität Dresden (DE)
- University of Tübingen (DE)
- Ludwig-Maximilians-Universität München (DE)
- University of Gothenburg (SE)
Publication Details
- Journal
- Movement Disorders
- Published
- 2025-01-10
- DOI
- https://doi.org/10.1002/mds.30112
- Citations
- 3
- Primary Topic
- Parkinson's Disease Mechanisms and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 4.17
Funders
- Sanofi
- Biogen
- Deutsche Forschungsgemeinschaft
- Volkswagen Foundation
- Deutsches Zentrum für Neurodegenerative Erkrankungen