A rare incidence of malignant pleural effusion in multiple myeloma

Multiple myeloma (MM) is one of the most common hematological malignancies. The incidence of pleural effusion (6%) as such is rare in patients with MM, and the incidence of myelomatous pleural effusion is even rarer (1%). The timely diagnosis of this entity is very important because these individuals have a poor overall prognosis. Diagnosis can be made by careful examination of pleural fluid cytology and can be confirmed by flow cytometry. We report a case of myelomatous pleural effusion diagnosed early and successfully managed.