Alignment of counseling around topical steroids will improve morbidity associated with lichen sclerosus

<h2>Abstract</h2> Ultrapotent topical steroids are the first-line treatment for lichen sclerosus, a chronic inflammatory disease that most commonly affects the genital and anal regions. Lichen sclerosus can cause profound morbidity and can progress to squamous cell carcinoma. Therefore, treatment is essential to mitigate these complications. Despite the accessibility, relative affordability, and safety profiles of topical steroids, many clinicians, pharmacists, and patients are hesitant to use them. This paper outlines the importance of chronic steroid use for managing lichen sclerosus to prevent disease sequelae and aims to educate readers on ways physicians and pharmacists can mitigate steroid phobia.

Authors

Publication Details

Journal
JAPhA Pharmacotherapy
Published
2024-12-01
DOI
https://doi.org/10.1016/j.japhar.2025.100010
Primary Topic
Genital Health and Disease
Type
article
Field-Weighted Citation Impact
0.00
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article

Alignment of counseling around topical steroids will improve morbidity associated with lichen sclerosus

Paras P. Vakharia, Margaret E. Greer, Melissa Mauskar
JAPhA Pharmacotherapy
Genital Health and Disease
article

Alignment of counseling around topical steroids will improve morbidity associated with lichen sclerosus

Paras P. Vakharia, Margaret E. Greer, Melissa Mauskar
article en

Abstract

<h2>Abstract</h2> Ultrapotent topical steroids are the first-line treatment for lichen sclerosus, a chronic inflammatory disease that most commonly affects the genital and anal regions. Lichen sclerosus can cause profound morbidity and can progress to squamous cell carcinoma. Therefore, treatment is essential to mitigate these complications. Despite the accessibility, relative affordability, and safety profiles of topical steroids, many clinicians, pharmacists, and patients are hesitant to use them. This paper outlines the importance of chronic steroid use for managing lichen sclerosus to prevent disease sequelae and aims to educate readers on ways physicians and pharmacists can mitigate steroid phobia.

JAPhA PharmacotherapyVol. 1(4)
Zero hunger
Openalex Percentile: Top 54%
Genital Health and Disease
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