Activation of mTOR/HK2 signaling mitigates effects of PYCR2 depletion in colorectal cells
Interference with PYCR2 corrected autophagy-dependent glycolysis levels in colorectal cancer cells via mTOR/HK2 signaling. Activation of mTOR/HK2 signaling mitigated the effects of PYCR2 depletion in colorectal cells.
Authors
- Nian Zhang (ORCID: https://orcid.org/0009-0004-4164-5929)
- Yuan Yuan (ORCID: https://orcid.org/0000-0002-7742-9433)
- Li Chen (ORCID: https://orcid.org/0000-0002-8013-5508)
- Yu Zhou (ORCID: https://orcid.org/0000-0002-1033-6742)
- Qianqian Huang (ORCID: https://orcid.org/0000-0001-6149-8154)
Institutions
- Zhuhai Hospital of Integrated Traditional Chinese and Western Medicine (CN)
Publication Details
- Journal
- Tissue and Cell
- Published
- 2025-01-10
- DOI
- https://doi.org/10.1016/j.tice.2025.102729
- Primary Topic
- Cancer, Hypoxia, and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 0.00