Retinal biomarkers for the risk of Alzheimer’s disease and frontotemporal dementia
Our findings provide preliminary empirical support for a relationship between prodromal changes in retinal layers and a higher risk of AD or FTD, suggesting that macular OCT may serve as a non-invasive, sensitive biomarker of high-risk years before the onset of dementia.
Authors
- Caimei Luo
- Yuzhu Gao (ORCID: https://orcid.org/0000-0002-4895-8002)
- Jiajie Cai (ORCID: https://orcid.org/0009-0007-6396-8501)
- Xiong Xiao (ORCID: https://orcid.org/0000-0001-6207-1611)
- Linyuan Qin (ORCID: https://orcid.org/0000-0002-2691-3903)
- Qiyong Gong (ORCID: https://orcid.org/0000-0002-5912-4871)
- Feng Yang (ORCID: https://orcid.org/0000-0002-4473-284X)
- Hui Gao (ORCID: https://orcid.org/0000-0001-5096-7023)
- Chunyan Luo
- Qin Chen (ORCID: https://orcid.org/0000-0002-5417-7835)
- Yingying Tang (ORCID: https://orcid.org/0000-0001-9603-6232)
- Yan Ren (ORCID: https://orcid.org/0000-0003-4519-397X)
- Shiyu Feng (ORCID: https://orcid.org/0009-0001-3060-541X)
- Hongbo Yin (ORCID: https://orcid.org/0009-0006-7990-9824)
- Ruihan Wang (ORCID: https://orcid.org/0000-0003-0562-2290)
- Ming Zhang (ORCID: https://orcid.org/0000-0002-1800-9041)
- Hanlin Cai (ORCID: https://orcid.org/0000-0003-1799-3435)
Institutions
- Sichuan University (CN)
- West China Medical Center of Sichuan University (CN)
- West China Hospital of Sichuan University (CN)
Publication Details
- Journal
- Frontiers in Aging Neuroscience
- Published
- 2025-01-10
- DOI
- https://doi.org/10.3389/fnagi.2024.1513302
- Citations
- 2
- Primary Topic
- Retinal Imaging and Analysis
- Type
- article
- Field-Weighted Citation Impact
- 2.72
Funders
- National Natural Science Foundation of China