Risk of Colorectal Cancer Associated With Frequency of Colorectal Polyp Diagnosis in Relatives
A higher frequency of colorectal polyp diagnosis in relatives is associated with a greater risk of CRC, especially early-onset CRC. This risk is independent of number of affected relatives or youngest age at polyp diagnosis. These findings underscore the need for more personalized CRC screening strategies that are tailored to individuals with a family history of polyp.
Authors
- Qunfeng Liang
- Jan Sundquist
- Mahdi Fallah (ORCID: https://orcid.org/0000-0002-6639-065X)
- Elham Kharazmi (ORCID: https://orcid.org/0000-0003-4919-6641)
- Kristina Sundquist (ORCID: https://orcid.org/0000-0001-8031-279X)
- Yuqing Hu (ORCID: https://orcid.org/0000-0001-8509-2271)
Institutions
- Heidelberg University (DE)
- University Hospital Heidelberg (DE)
- National Center for Tumor Diseases (DE)
- Healthcare in Sweden (SE)
- Primary Health Care (QA)
Publication Details
- Journal
- Gastroenterology
- Published
- 2025-01-10
- DOI
- https://doi.org/10.1053/j.gastro.2024.12.030
- Citations
- 10
- Primary Topic
- Colorectal Cancer Screening and Detection
- Type
- article
- Field-Weighted Citation Impact
- 10.45
Funders
- China Scholarship Council