Interaction between genetic risk score and dietary carbohydrate intake on high-density lipoprotein cholesterol levels: Findings from the study of obesity, nutrition, genes and social factors (SONGS)
Our results suggest that young adults who consume a higher carbohydrate diet and have a higher GRS have a lower HDL-C concentration, which in turn is linked to cardiovascular diseases, and indicate that personalised nutrition strategies targeting a reduction in carbohydrate intake might be beneficial for these individuals.
Authors
- Lisa Methven
- Claudia Beatriz Murray (ORCID: https://orcid.org/0000-0001-6403-075X)
- Litai Liu
- Ramatu Wuni
- Mary E. Penny (ORCID: https://orcid.org/0000-0001-5501-9399)
- Richard Nunes (ORCID: https://orcid.org/0000-0003-0829-4130)
- Marta Favara (ORCID: https://orcid.org/0000-0002-5764-4654)
- Karani S. Vimaleswaran (ORCID: https://orcid.org/0000-0002-8485-8930)
- Ariana Musa de Aquino (ORCID: https://orcid.org/0000-0002-8407-2612)
- Katherine Curi-Quinto (ORCID: https://orcid.org/0000-0002-2233-8251)
- Julie A. Lovegrove (ORCID: https://orcid.org/0000-0001-7633-9455)
- D. Espinoza (ORCID: https://orcid.org/0009-0000-1874-4145)
- Miguel Ángel Aguilar-Luis (ORCID: https://orcid.org/0000-0001-7023-3190)
- Juana del Valle-Mendoza (ORCID: https://orcid.org/0000-0002-6011-5040)
- Alan Sánchez (ORCID: https://orcid.org/0000-0001-7109-8613)
Institutions
- Peruvian University of Applied Sciences (PE)
- University of Oxford (GB)
- Group for the Analysis of Development (PE)
- Instituto de Investigación Nutricional (PE)
- University of Reading (GB)
Publication Details
- Journal
- Clinical Nutrition ESPEN
- Published
- 2025-01-10
- DOI
- https://doi.org/10.1016/j.clnesp.2024.12.027
- Citations
- 4
- Primary Topic
- Diet and metabolism studies
- Type
- article
- Field-Weighted Citation Impact
- 4.66
Funders
- University of Oxford
- University of Reading
- Consejo Nacional de Ciencia, Tecnología e Innovación Tecnológica
- Foreign, Commonwealth and Development Office
- Medical Research Council
- Medical Research Foundation