Triptolide exhibits dual anti-tumor effects through inhibiting autophagy and extracellular matrix activation in pancreatic cancer
These findings indicate that triptolide plays a dual antitumor role against tumor cells and CAFs, thus providing new insights into treating pancreatic cancer in the future.
Authors
- J.-X. Gu (ORCID: https://orcid.org/0000-0003-2251-7062)
- Hongzhen Li (ORCID: https://orcid.org/0000-0001-6393-3009)
- Quan Zhou (ORCID: https://orcid.org/0000-0001-6941-9887)
- Xiaoping Zou (ORCID: https://orcid.org/0000-0003-0194-4567)
- Shanshan Shen (ORCID: https://orcid.org/0000-0001-9967-7764)
- Shuang Nie
- Zhao Shi
- Siqi Zhou (ORCID: https://orcid.org/0009-0000-5436-1256)
Institutions
- Nanjing University of Chinese Medicine (CN)
- Xuzhou Medical College (CN)
- Nanjing Drum Tower Hospital (CN)
- Second People’s Hospital of Huai’an (CN)
- Nanjing Medical University (CN)
Publication Details
- Journal
- Journal of Cancer Research and Therapeutics
- Published
- 2024-12-01
- DOI
- https://doi.org/10.4103/jcrt.jcrt_186_24
- Primary Topic
- Natural Compounds in Disease Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00