Comprehensive transthoracic echocardiographic evaluation of doxorubicin-induced cardiotoxicity: a multimodal imaging approach in an animal model
Our rat model of DOX-induced cardiotoxicity demonstrates that volumetric changes are more pronounced. Both 4D- and M-mode imaging techniques proved effective and reliable compared with the standard B-mode approach, with minimal interobserver variability, indicating strong reproducibility.
Authors
- Sibren Haesen (ORCID: https://orcid.org/0000-0002-7940-3456)
- Virginie Bito (ORCID: https://orcid.org/0000-0003-0986-7906)
- Dorien Deluyker (ORCID: https://orcid.org/0000-0002-1645-319X)
- Lisa Steegen
Institutions
- Organ Recovery Systems (Belgium) (BE)
- Hasselt University (BE)
Publication Details
- Journal
- European Heart Journal - Imaging Methods and Practice
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1093/ehjimp/qyaf006
- Citations
- 4
- Primary Topic
- Chemotherapy-induced cardiotoxicity and mitigation
- Type
- article
- Field-Weighted Citation Impact
- 5.55
Funders
- Fonds Wetenschappelijk Onderzoek
- Vlaamse regering