Pharmacodynamic Evaluation of Polyherbs and its Formulation for Antitussive Activity Using Citric Acid Induced in Guinea Pig

This review article focuses on the pharmacodynamic evaluation of polyherbal formulations for antitussive activity, utilising a citric acid-induced cough model in guinea pigs. The study explores various polyherbs traditionally used in cough treatment, aiming to validate their efficacy through scientific methods. By inducing coughing in guinea pigs with citric acid, the antitussive effects of different herbal combinations are assessed in comparison to standard cough suppressants. The review emphasizes the potential advantages of polyherbs, such as synergistic effects, reduced side effects, and natural origin, making them promising candidates for cough management. Furthermore, the article highlights the importance of evaluating dosage, formulation, and bioactive components to optimize therapeutic outcomes. This comprehensive review contributes to the growing body of evidence supporting the use of polyherbal remedies in the treatment of cough-related disorders.